2. For the autosomal recessive condition Cystic Fibrosis, a population is studied to see if it is in HardyWeinberg equilibrium (HWE). Define Alleles A randomly mating population of 1000 individuals is comprised of: A= non-disease 812AA176Aa12 aa a= cystic fibrosis Calculate the allele frequencies and use these to predict the expected genotype freq

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2. For the autosomal recessive condition Cystic Fibrosis, a population is studied to see if it is in HardyWeinberg equilibrium (HWE). Define Alleles A randomly mating population of 1000 individuals is comprised of:

A =

non-disease

812 AA 176 Aa 12

aa

a =

cystic fibrosis Calculate the allele frequencies and use these to predict the expected genotype frequencies if the population is in HWE. Is the population in HWE? Answer by calculating the expected number of each genotype under HWE for 1000 individuals. Compare these to the observed numbers in the population above. Show your work.

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