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(Solved): 2. Separation processes for bioproduct (15 marks) A solution of monoclonal an ...
2. Separation processes for bioproduct (15 marks) A solution of monoclonal antibody, with a concentration of , is fed at a flow rate of ( equals the first 5 digits of your student ID). The following flowsheet has been employed to remove impurities and concentrate the antibody to . a) Briefly introduce the function of 5 main unit operations in the flowsheet and tell how the antibody stream is leaving from each operation. b) Based on the data given, calculate the yield of recovery at the end. c) List three major challenges/problems making this separation costly.
Expert Answer
a) The five main unit operations in the flowsheet and their functions are as follows: Filtration is used to remove solid impurities from the solution. The solution is passed through a filter medium that retains the solid particles, allowing the purified antibody stream to pass through. The antibody stream leaving this operation is free from solid impurities.