7 Multiple Answer 1 point How would you guess that the binding of antigen to the variable region of a B-cell receptor might lead to that cells proliferation and differentiation into plasma cells and memory cells? A conformational change in transmembrane domain of the B-cell receptor contacting a cytoplasmic protein By triggering phosphorylation of

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7 Multiple Answer 1 point How would you guess that the binding of antigen to the variable region of a B-cell receptor might lead to that cells proliferation and differentiation into plasma cells and memory cells? A conformational change in transmembrane domain of the B-cell receptor contacting a cytoplasmic protein By triggering phosphorylation of a protein in that cell to expose a nuclear localization signal By binding to the B-cell receptor after it has been secreted as an antibody By binding to the B-cell receptor prior to completion of VDJ-recombination By ultimately leading to differential expression of genes in that cell involved in differentiation

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