The diagram below shows the LOD scores calculated at various genetic distances (recombination fraction, or theta) for eight adjacent genetic markers genotyped in a family (Family 1), in which an autosomal, dominantly-inherited disease is segregating. Each of the markers has been genotyped in all family members. (inf. = infinity) a) Which of these genetic markers indicate that this region of the chromosome is linked to the disease? Explain. [4 marks] b) Which of these markers is likely to be the closest to the disease gene? Explain. [3 marks] c) All of the markers were genotyped in all of the family members yet they have different LOD scores from one another in this analysis. Why this is so? [2 marks] d) How do we know that none of these genetic markers segregates exactly the same as the disease gene in this family? Explain.