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(Solved): Two ligands, A and B, bind to two different conformations of the enzyme X. The ligand A is the enzym ...
Two ligands, A and B, bind to two different conformations of the enzyme X. The ligand A is the enzyme’s substrate, whereas ligand B binds to a remote allosteric site. How does ligand B affect the affinity of substrate A?
Explanation:The effect of ligand B on the affinity of substrate A.Proteins that catalyze chemical reactions in living organisms are known as enzymes. The binding of a ligand to an enzyme, such as a substrate or an allosteric modulator, can change its conformation and, as a result, its activity. Enzyme X, for example, has two distinct conformations that can be bound by ligands A and B.1. Positive allosteric regulation2. Negative allosteric regulationNow we will discuss each one in detail explanation.