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(Solved): Very polar compounds are sometime purified by reverse phase chromatography where the stationary phas ...



Very polar compounds are sometime purified by reverse phase chromatography where
the stationary phase is very nonpolar while the solvent is very polar. Why might one
want to use this technique with extremely polar compounds? Again, use the number of
intermolecular force interactions these kinds of compounds create with the stationary
phase in your answer. Is separation better if at least some of the compounds have high Rf
values or if they all have low Rf values? So how does “reversing the polarity” (compared
to the experiment you ran) allow this to happen?



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Reverse phase chromatography is used for the purification of extremely polar compounds because polar compounds interact more strongly with nonpolar st
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